Collagen alpha-1(I) chain

BE0000025ProteinHumansCOL1A1

Type I collagen is a member of group I collagen (fibrillar forming collagen). It is acted on by 7 drugs in DrugBank.

Gene name
COL1A1
UniProtKB entry
P02452Swiss-Prot
Cellular location
Secreted, extracellular space, extracellular matrix
Residues / weight
1,464 residues · 138,911 Da
Also known as
Alpha-1 type I collagen

Resolves to

Protein
UniProtP02452UniProt nameCO1A1_HUMAN
Gene
HGNCHGNC:2197NCBI Gene1277GenBank1418928GeneCardsCOL1A1
Pharmacology
KEGGhsa:1277
Structure
PDB1Q7DPDB2LLPPDB3EJH
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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32GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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114+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Collagen alpha-1(I) chain, how selective are they, and which programs against it are still in active trials?

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