High affinity immunoglobulin epsilon receptor subunit gamma

BE0000049ProteinHumansFCER1G

Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. It is acted on by 3 drugs in DrugBank.

Gene name
FCER1G
UniProtKB entry
P30273Swiss-Prot
Cellular location
Cell membrane
Residues / weight
86 residues · 9,667 Da
Also known as
Fc receptor gamma-chain · Fc-epsilon RI-gamma · FceRI gamma · FcRgamma · IgE Fc receptor subunit gamma

Resolves to

Protein
UniProtP30273UniProt nameFCERG_HUMAN
Gene
HGNCHGNC:3611NCBI Gene2207GenBank182488GeneCardsFCER1G
Pharmacology
KEGGhsa:2207
Structure
PDB7Q5TPDB8YVUPDB8YWA
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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17GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on High affinity immunoglobulin epsilon receptor subunit gamma, how selective are they, and which programs against it are still in active trials?

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