This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Fucose
- DrugBank Accession Number
- DB15236
- Background
Fucose is under investigation in clinical trial NCT03354533 (Study of ORL-1F (L-fucose) in Patients With Leukocyte Adhesion Deficiency Type II).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
Structure for Fucose (DB15236)
- Weight
- Average: 164.157
Monoisotopic: 164.068473486 - Chemical Formula
- C6H12O5
- Synonyms
- L-FUCOSE
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 28RYY2IV3F
- CAS number
- 2438-80-4
- InChI Key
- PNNNRSAQSRJVSB-KCDKBNATSA-N
- InChI
- InChI=1S/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1
- IUPAC Name
- (2S,3R,4R,5S)-2,3,4,5-tetrahydroxyhexanal
- SMILES
- C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0062489
- ChemSpider
- 2299091
- 2466731
- ChEBI
- 48204
- ZINC
- ZINC000100015850
- Wikipedia
- Fucose
Clinical Trials
- Clinical Trials
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Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data3 Recruiting Treatment Leukocyte Adhesion Deficiency Syndrome 1 somestatus stop reason just information to hide 1, 2 Completed Treatment Congenital Disorder of Glycosylation IIc 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 258.0 mg/mL ALOGPS logP -2 ALOGPS logP -2.5 Chemaxon logS 0.2 ALOGPS pKa (Strongest Acidic) 12.31 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 97.99 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 35.8 m3·mol-1 Chemaxon Polarizability 15.22 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS splash10-05n1-9300000000-067ca5ef1dbdc796efe0 Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-004i-2900000000-7beae0d1b67501fcb819 Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0a4m-9300000000-d8665ec56300b843aef8 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-0adi-9100000000-1352cae092fb635a679b Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-052e-9000000000-d4dc17807a67e32ab31f Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-0005-9000000000-3aa9f6c350d846f38146 Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-006y-9000000000-252ac3ef76a19fc26d87 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 137.6873684 predictedDarkChem Lite v0.1.0 [M-H]- 134.0783684 predictedDarkChem Lite v0.1.0 [M-H]- 135.0738 predictedDeepCCS 1.0 (2019) [M+H]+ 138.7138684 predictedDarkChem Lite v0.1.0 [M+H]+ 136.2434684 predictedDarkChem Lite v0.1.0 [M+H]+ 137.44273 predictedDeepCCS 1.0 (2019) [M+Na]+ 137.7093684 predictedDarkChem Lite v0.1.0 [M+Na]+ 134.1415684 predictedDarkChem Lite v0.1.0 [M+Na]+ 143.9229 predictedDeepCCS 1.0 (2019)
Drug created at May 20, 2019 15:03 / Updated at June 12, 2020 16:53