Growth hormone receptor

BE0000075ProteinHumansGHR

Receptor for pituitary gland growth hormone (GH1) involved in regulating postnatal body growth (PubMed:1549776, PubMed:2825030, PubMed:8943276). It is acted on by 12 drugs in DrugBank.

Gene name
GHR
UniProtKB entry
P10912Swiss-Prot
Cellular location
Cell membrane
Residues / weight
638 residues · 71,499 Da
Also known as
GH receptor · Somatotropin receptor

Resolves to

Protein
UniProtP10912UniProt nameGHR_HUMAN
Gene
HGNCHGNC:4263NCBI Gene2690GenBank31738GeneCardsGHR
Pharmacology
IUPHAR/GtoPdb1720KEGGhsa:2690
Structure
PDB1A22PDB1AXIPDB1HWG
Drugs

What you can answer from here — as of September 07, 2019

12DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
28GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
72+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Growth hormone receptor, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In