Creatine kinase B-type

BE0000082ProteinHumansCKB

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate) (PubMed:8186255). It is acted on by 4 drugs in DrugBank.

Gene name
CKB
UniProtKB entry
P12277Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
381 residues · 42,644 Da
Also known as
2.7.3.2 · B-CK · Brain creatine kinase · CKBB · CPK-B

Resolves to

Protein
UniProtP12277UniProt nameKCRB_HUMAN
Gene
HGNCHGNC:1991NCBI Gene1152GenBank180572GeneCardsCKB
Pharmacology
KEGGhsa:1152
Structure
PDB3B6RPDB3DRBPDB3DRE
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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24+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Creatine kinase B-type, how selective are they, and which programs against it are still in active trials?

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