An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
- Mechanism
- Curator reviewed
In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosphocreatine (PCr). Phosphocreatine binds with adenosine diphosphate to convert it back to ATP (adenosine triphosphate), an important cellular energy source for short term ATP needs prior to oxidative phosphorylation.
- Primary indication
- For nutritional supplementation, also for treating dietary shortage or imbalance.Curator reviewed
- Formula / weight
- C4H9N3O2 · 131.1332 g/mol (avg)
- Also known as
- Creatin · Kreatin
Resolves to
CVSVTCORWBXHQV-UHFFFAOYSA-NSMILESCN(CC(O)=O)C(N)=NWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Creatine, and which of those have an active Phase 3 trial?
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