Creatine kinase U-type, mitochondrial

BE0000171ProteinHumansCKMT1A

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). It is acted on by 2 drugs in DrugBank.

Gene name
CKMT1A
UniProtKB entry
P12532Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
417 residues · 47,036 Da
Also known as
2.7.3.2 · Acidic-type mitochondrial creatine kinase · CKMT · Mia-CK · U-MtCK

Resolves to

Protein
UniProtP12532UniProt nameKCRU_HUMAN
Gene
HGNCHGNC:1995NCBI Gene548596GenBank180590GeneCardsCKMT1B
Pharmacology
KEGGhsa:548596
Structure
PDB1QK1PDB9B04PDB9B05
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Creatine kinase U-type, mitochondrial, how selective are they, and which programs against it are still in active trials?

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