Scavenger receptor class B member 1

BE0000189ProteinHumansSCARB1

Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). It is acted on by 6 drugs in DrugBank.

Gene name
SCARB1
UniProtKB entry
Q8WTV0Swiss-Prot
Cellular location
Cell membrane
Residues / weight
552 residues · 60,877 Da
Also known as
CD36 and LIMPII analogous 1 · CD36 antigen-like 1 · CD36L1 · CLA-1 · CLA1

Resolves to

Protein
UniProtQ8WTV0UniProt nameSCRB1_HUMAN
Gene
HGNCHGNC:1664NCBI Gene949GenBank397607GeneCardsSCARB1
Pharmacology
KEGGhsa:949
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Scavenger receptor class B member 1, how selective are they, and which programs against it are still in active trials?

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