Sodium channel protein type 11 subunit alpha

BE0000192ProteinHumansSCN11A

Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. It is acted on by 10 drugs in DrugBank.

Gene name
SCN11A
UniProtKB entry
Q9UI33Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,791 residues · 204,920 Da
Also known as
hNaN · Peripheral nerve sodium channel 5 · PN5 · SCN12A · Sensory neuron sodium channel 2

Resolves to

Protein
UniProtQ9UI33UniProt nameSCNBA_HUMAN
Gene
HGNCHGNC:10583NCBI Gene11280GenBank6572950GeneCardsSCN11A
Pharmacology
IUPHAR/GtoPdb586KEGGhsa:11280
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium channel protein type 11 subunit alpha, how selective are they, and which programs against it are still in active trials?

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