Choline/ethanolamine kinase

BE0000237ProteinHumansCHKB

Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis. It is acted on by 4 drugs in DrugBank.

Gene name
CHKB
UniProtKB entry
Q9Y259Swiss-Prot
Residues / weight
395 residues · 45,271 Da
Also known as
CHETK · CHKL · Choline kinase beta · Choline kinase-like protein · choline/ethanolamine kinase beta

Resolves to

Protein
UniProtQ9Y259UniProt nameCHKB_HUMAN
Gene
HGNCHGNC:1938NCBI Gene1120GenBank5509940GeneCardsCHKB
Pharmacology
KEGGhsa:1120
Structure
PDB2IG7PDB3FEGPDB3LQ3
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1GO termFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
17+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Choline/ethanolamine kinase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In