Lipoprotein lipase

BE0000239ProteinHumansLPL

Key enzyme in triglyceride metabolism. It is acted on by 15 drugs in DrugBank.

Gene name
LPL
UniProtKB entry
P06858Swiss-Prot
Cellular location
Cell membrane
Residues / weight
475 residues · 53,162 Da
Also known as
3.1.1.34 · LIPD · LPL · Phospholipase A1

Resolves to

Protein
UniProtP06858UniProt nameLIPL_HUMAN
Gene
HGNCHGNC:6677NCBI Gene4023GenBank307138GeneCardsLPL
Pharmacology
KEGGhsa:4023
Structure
PDB6E7KPDB6OAUPDB6OAZ
Drugs

What you can answer from here — as of September 07, 2019

15DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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26GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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96+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Lipoprotein lipase, how selective are they, and which programs against it are still in active trials?

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