Beta-1,4-galactosyltransferase 1

BE0000259ProteinHumansB4GALT1

Galactosyltransferase acting in the Golgi stacks. It is acted on by 6 drugs in DrugBank.

Gene name
B4GALT1
UniProtKB entry
P15291Swiss-Prot
Cellular location
Golgi apparatus, Golgi stack membrane
Residues / weight
398 residues · 43,920 Da
Also known as
2.4.1.- · b4Gal-T1 · Beta-1,4-GalTase 1 · Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase · Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

Resolves to

Protein
UniProtP15291UniProt nameB4GT1_HUMAN
Gene
HGNCHGNC:924NCBI Gene2683GenBank29424GeneCardsB4GALT1
Pharmacology
KEGGhsa:2683
Structure
PDB2AE7PDB2AECPDB2AES
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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31+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Beta-1,4-galactosyltransferase 1, how selective are they, and which programs against it are still in active trials?

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