Adenylate cyclase type 1

BE0000269ProteinHumansADCY1

Catalyzes the formation of the signaling molecule cAMP in response to G protein signaling. It is acted on by 6 drugs in DrugBank.

Gene name
ADCY1
UniProtKB entry
Q08828Swiss-Prot
Cellular location
Membrane
Residues / weight
1,119 residues · 123,439 Da
Also known as
4.6.1.1 · Adenylate cyclase type I · Adenylyl cyclase 1 · ATP pyrophosphate-lyase 1 · Ca(2+)/calmodulin-activated adenylyl cyclase

Resolves to

Protein
UniProtQ08828UniProt nameADCY1_HUMAN
Gene
HGNCHGNC:232NCBI Gene107GenBank41472630GeneCardsADCY1
Pharmacology
IUPHAR/GtoPdb1278KEGGhsa:107
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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17+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Adenylate cyclase type 1, how selective are they, and which programs against it are still in active trials?

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