Voltage-dependent L-type calcium channel subunit beta-1

BE0000303ProteinHumansCACNB1

Regulatory subunit of L-type calcium channels (PubMed:1309651, PubMed:15615847, PubMed:8107964). It is acted on by 7 drugs in DrugBank.

Gene name
CACNB1
UniProtKB entry
Q02641Swiss-Prot
Cellular location
Cell membrane, sarcolemma
Residues / weight
598 residues · 65,713 Da
Also known as
CAB1 · CACNLB1 · Calcium channel voltage-dependent subunit beta 1

Resolves to

Protein
UniProtQ02641UniProt nameCACB1_HUMAN
Gene
HGNCHGNC:1401NCBI Gene782GenBank179806GeneCardsCACNB1
Pharmacology
KEGGhsa:782
Structure
PDB7VFSPDB7VFUPDB7VFV
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-dependent L-type calcium channel subunit beta-1, how selective are they, and which programs against it are still in active trials?

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