Transcobalamin-2

BE0000362ProteinHumansTCN2

Primary vitamin B12-binding and transport protein. It is acted on by 3 drugs in DrugBank.

Gene name
TCN2
UniProtKB entry
P20062Swiss-Prot
Cellular location
Secreted
Residues / weight
427 residues · 47,535 Da
Also known as
TC II · TC-2 · TC2 · TCII · Transcobalamin II

Resolves to

Protein
UniProtP20062UniProt nameTCO2_HUMAN
Gene
HGNCHGNC:11653NCBI Gene6948GenBank339196GeneCardsTCN2
Pharmacology
KEGGhsa:6948
Structure
PDB2BB5PDB4ZRPPDB4ZRQ
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Transcobalamin-2, how selective are they, and which programs against it are still in active trials?

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