Cobalamin

Star0

DB14098ApprovedInvestigationalSmall molecule

Cobalamin: Overview.

Mechanism: Pharmacologically active on Methionine synthase and Methylmalonyl-CoA mutase, mitochondrial
Curator reviewed
Formula / weight: C₆₂H₈₈CoN₁₃O₁₄P · 1329.37 g/mol (avg)
First approval: Canada, 2005
Also known as: vitamin B12

Resolves to

Compound

UNII8406EY2OQACAS13408-78-1

Clinical / RWD

RxNorm11248

Structure

InChIKeyASARMUCNOOHMLO-WLORSUFZSA-LSMILES

[Co++].[H]N([H])C(=O)CC[C@@H]1C2=N\C(=C(C)/C3=N[C@@](C)([C@]4([H])[N-]\C(=C(C)/C5=N/C(=C\2)/C(C)(C)[C@@H]5CCC(=O)N([H])[H])[C@](C)(CCC(=O)N([H])C[C@H](C)OP([O-])(=O)O[C@@H]2[C@@H](CO)O[C@@H]([C@@H]2O)N2C=NC5=C2C=C(C)C(C)=C5)[C@H]4CC(=O)N([H])[H])[C@@](C)(CC(=O)N([H])[H])[C@@H]3CCC(=O)N([H])[H])\[C@@]1(C)CC(=O)N([H])[H]

Targets

Q99707MTRP22033MMUT

Transporters

O60494CUBNP06129btuBO14678ABCD4Q9NPF0CD320

What you can answer from here — as of July 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4TransportersSubstrate / inhibitor direction, not just membership

Listed above

1Drug interactionStructured to mechanism, not free text

112Clinical trialsPhase, status and sponsor resolved per trial

26Marketed productsAcross 2 countries and 15 labellers

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with Cobalamin, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account