Riboflavin kinase

BE0000370ProteinHumansRFK

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. It is acted on by 2 drugs in DrugBank.

Gene name
RFK
UniProtKB entry
Q969G6Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
155 residues · 17,623 Da
Also known as
2.7.1.26 · ATP:riboflavin 5'-phosphotransferase · Flavokinase

Resolves to

Protein
UniProtQ969G6UniProt nameRIFK_HUMAN
Gene
HGNCHGNC:30324NCBI Gene55312GenBank7023634GeneCardsRFK
Pharmacology
KEGGhsa:55312
Structure
PDB1NB0PDB1NB9PDB1P4M
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Riboflavin kinase, how selective are they, and which programs against it are still in active trials?

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