Alpha-N-acetylglucosaminidase

BE0000391ProteinHumansNAGLU

Involved in the degradation of heparan sulfate. It is acted on by 3 drugs in DrugBank.

Gene name
NAGLU
UniProtKB entry
P54802Swiss-Prot
Cellular location
Lysosome
Residues / weight
743 residues · 82,265 Da
Also known as
3.2.1.50 · N-acetyl-alpha-glucosaminidase · NAG · UFHSD1

Resolves to

Protein
UniProtP54802UniProt nameANAG_HUMAN
Gene
HGNCHGNC:7632NCBI Gene4669GenBank1171229GeneCardsNAGLU
Pharmacology
KEGGhsa:4669
Structure
PDB4XWH
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Alpha-N-acetylglucosaminidase, how selective are they, and which programs against it are still in active trials?

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