Neuronal acetylcholine receptor subunit alpha-10

BE0000411ProteinHumansCHRNA10

Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits. It is acted on by 9 drugs in DrugBank.

Gene name
CHRNA10
UniProtKB entry
Q9GZZ6Swiss-Prot
Cellular location
Synaptic cell membrane
Residues / weight
450 residues · 49,704 Da
Also known as
NACHR alpha-10 · NACHRA10 · Nicotinic acetylcholine receptor subunit alpha-10

Resolves to

Protein
UniProtQ9GZZ6UniProt nameACH10_HUMAN
Gene
HGNCHGNC:13800NCBI Gene57053GenBank12053839GeneCardsCHRNA10
Pharmacology
IUPHAR/GtoPdb470KEGGhsa:57053
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Neuronal acetylcholine receptor subunit alpha-10, how selective are they, and which programs against it are still in active trials?

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