Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

BE0000423ProteinHumansSLC6A14

Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract. It is acted on by 6 drugs in DrugBank.

Gene name
SLC6A14
UniProtKB entry
Q9UN76Swiss-Prot
Cellular location
Membrane
Residues / weight
642 residues · 72,152 Da
Also known as
Amino acid transporter ATB0+ · Solute carrier family 6 member 14

Resolves to

Protein
UniProtQ9UN76UniProt nameS6A14_HUMAN
Gene
HGNCHGNC:11047NCBI Gene11254GenBank5732680GeneCardsSLC6A14
Pharmacology
IUPHAR/GtoPdb937KEGGhsa:11254
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+), how selective are they, and which programs against it are still in active trials?

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