Interferon gamma receptor 2

BE0000467ProteinHumansIFNGR2

Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:7673114, PubMed:8124716). It is acted on by 3 drugs in DrugBank.

Gene name
IFNGR2
UniProtKB entry
P38484Swiss-Prot
Cellular location
Cell membrane
Residues / weight
337 residues · 37,806 Da
Also known as
AF-1 · IFN-gamma receptor 2 · IFN-gamma-R-beta · IFN-gamma-R2 · IFNGT1

Resolves to

Protein
UniProtP38484UniProt nameINGR2_HUMAN
Gene
HGNCHGNC:5440NCBI Gene3460GenBank463550GeneCardsIFNGR2
Pharmacology
KEGGhsa:3460
Structure
PDB5EH1PDB6E3KPDB6E3L
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interferon gamma receptor 2, how selective are they, and which programs against it are still in active trials?

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