Thyrotropin receptor

BE0000490ProteinHumansTSHR

Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). It is acted on by 2 drugs in DrugBank.

Gene name
TSHR
UniProtKB entry
P16473Swiss-Prot
Cellular location
Cell membrane
Residues / weight
764 residues · 86,843 Da
Also known as
LGR3 · Thyroid-stimulating hormone receptor · TSH-R

Resolves to

Protein
UniProtP16473UniProt nameTSHR_HUMAN
Gene
HGNCHGNC:12373NCBI Gene7253GenBank903760GeneCardsTSHR
Pharmacology
IUPHAR/GtoPdb255KEGGhsa:7253
Structure
PDB2XWTPDB3G04PDB7T9I
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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74+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thyrotropin receptor, how selective are they, and which programs against it are still in active trials?

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