This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Thyrotropin is a medication indicated in thyroid stimulation before radioactive iodine ablation or for thyroid imaging.

Generic Name
Thyrotropin
DrugBank Accession Number
DB15263
Background

Thyrotropin is under investigation in clinical trial NCT01348191 (Detection of Thyrotrophin Receptor in Human Myometrium).

Type
Biotech
Groups
Investigational
Synonyms
  • THYROTROPHIN

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Therapies
Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcalabrutinibThe therapeutic efficacy of Thyrotropin can be decreased when used in combination with Acalabrutinib.
AcebutololThe risk or severity of adverse effects can be increased when Acebutolol is combined with Thyrotropin.
AcetohexamideThe therapeutic efficacy of Acetohexamide can be decreased when used in combination with Thyrotropin.
AfatinibThe therapeutic efficacy of Thyrotropin can be decreased when used in combination with Afatinib.
AldesleukinThe therapeutic efficacy of Thyrotropin can be decreased when used in combination with Aldesleukin.
AlectinibThe therapeutic efficacy of Thyrotropin can be decreased when used in combination with Alectinib.
Aminosalicylic acidThe therapeutic efficacy of Thyrotropin can be decreased when used in combination with Aminosalicylic acid.
AmitriptylineThe risk or severity of Cardiac Arrhythmia can be increased when Thyrotropin is combined with Amitriptyline.
AmitriptylinoxideThe risk or severity of Cardiac Arrhythmia can be increased when Thyrotropin is combined with Amitriptylinoxide.
AmoxapineThe risk or severity of Cardiac Arrhythmia can be increased when Thyrotropin is combined with Amoxapine.
Interactions
Identify potential medication risks
Easily compare up to 40 drugs with our drug interaction checker.
Get severity rating, description, and management advice.
Learn more
Food Interactions
Not Available

Products

Products2
Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now

Categories

ATC Codes
V04CJ01 — Thyrotropin
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
02KSI6Z9AK
CAS number
9002-71-5

References

General References
  1. AIFA: Thyrogen (Thyrotropin) Intramuscular Injection [Link]
RxNav
10579
Wikipedia
Thyroid-stimulating_hormone

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentBenign Nontoxic and Toxic Goiter / Graves' Disease1
2CompletedTreatmentGoiter, Nodular1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, powder, for solutionIntramuscular; Parenteral
Injection, powder, for solutionIntramuscular; Parenteral0.9 MG
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at May 20, 2019 15:05 / Updated at May 14, 2021 01:07