Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in diagnostic testing for thyroid cancer and alongside radioactive agents to destroy thyroid tissue. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer.
- Mechanism
- Curator reviewed
Thyrotropin Alfa binds to the thyrotropin receptors found on any residual thyroid cells or tissues. This stimulates radioactive iodine uptake for better radiodiagnostic imaging.
- Primary indication
- For detection of residueal or recurrent thyroid cancerCurator reviewed · 2 structured indications
- Formula / weight
- C975H1513N267O304S26 · 22672.9 Da
- First approval
- Canada, 2024 · United States, 1998 · European Union, 2020
- Also known as
- Recombinant Human Thyroid Stimulating Hormone · Recombinant thyrotropin alfa · rhTSH · rTSH · Thyrotropin alpha
- Code names
- GX-30
- Brand names
Resolves to
Clinical / RWD
Targets
What you can answer from here — as of July 17, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Thyrotropin alfa, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account