Choline-phosphate cytidylyltransferase B

BE0000494ProteinHumansPCYT1B

Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. It is acted on by 5 drugs in DrugBank.

Gene name
PCYT1B
UniProtKB entry
Q9Y5K3Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
369 residues · 41,940 Da
Also known as
2.7.7.15 · CCT B · CCT-beta · CCTB · CT B

Resolves to

Protein
UniProtQ9Y5K3UniProt namePCY1B_HUMAN
Gene
HGNCHGNC:8755NCBI Gene9468GenBank3153239GeneCardsPCYT1B
Pharmacology
KEGGhsa:9468
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Choline-phosphate cytidylyltransferase B, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In