Cholesterol

DB04540ApprovedInvestigationalWithdrawnSmall molecule

The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.

Chemical structure of Cholesterol
Formula / weight
C27H46O · 386.6535 g/mol (avg)
Also known as
Cholesterin
Code names
NSC-8798

Resolves to

Compound
UNII97C5T2UQ7JCAS57-88-5ChEMBLCHEMBL112570ChEBI16113PubChem5997KEGGD00040
Clinical / RWD
RxNorm2438
Structure
InChIKeyHVYWMOMLDIMFJA-DPAQBDIFSA-NSMILES[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
Targets
Q9Y5K3PCYT1BQ14994NR1I3P11473VDRQ9ULY5CLEC4EP35398RORA
Transporters
P08183ABCB1Q9UNQ0ABCG2

What you can answer from here — as of September 23, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
2TransportersSubstrate / inhibitor direction, not just membership
Listed above
101Drug interactionsStructured to mechanism, not free text
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28Clinical trialsPhase, status and sponsor resolved per trial
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8+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Cholesterol, and which of those have an active Phase 3 trial?

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