Potassium-transporting ATPase subunit beta

BE0000619ProteinHumansATP4B

The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. It is acted on by 8 drugs in DrugBank.

Gene name
ATP4B
UniProtKB entry
P51164Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
291 residues · 33,367 Da
Also known as
Gastric H(+)/K(+) ATPase subunit beta · Proton pump beta chain

Resolves to

Protein
UniProtP51164UniProt nameATP4B_HUMAN
Gene
HGNCHGNC:820NCBI Gene496GenBank184105GeneCardsATP4B
Pharmacology
KEGGhsa:496
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Potassium-transporting ATPase subunit beta, how selective are they, and which programs against it are still in active trials?

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