Tyrosine aminotransferase

BE0000692ProteinHumansTAT

Transaminase involved in tyrosine breakdown. It is acted on by 4 drugs in DrugBank.

Gene name
TAT
UniProtKB entry
P17735Swiss-Prot
Residues / weight
454 residues · 50,399 Da
Also known as
2.6.1.5 · L-tyrosine:2-oxoglutarate aminotransferase · TAT

Resolves to

Protein
UniProtP17735UniProt nameATTY_HUMAN
Gene
HGNCHGNC:11573NCBI Gene6898GenBank36713GeneCardsTAT
Pharmacology
KEGGhsa:6898
Structure
PDB3DYD
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tyrosine aminotransferase, how selective are they, and which programs against it are still in active trials?

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