Creatine kinase M-type

BE0000714ProteinHumansCKM

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). It is acted on by 4 drugs in DrugBank.

Gene name
CKM
UniProtKB entry
P06732Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
381 residues · 43,101 Da
Also known as
2.7.3.2 · CKMM · CPK-M · Creatine kinase M chain · Creatine phosphokinase M-type

Resolves to

Protein
UniProtP06732UniProt nameKCRM_HUMAN
Gene
HGNCHGNC:1994NCBI Gene1158GenBank180576GeneCardsCKM
Pharmacology
KEGGhsa:1158
Structure
PDB1I0EPDB7BF2
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Creatine kinase M-type, how selective are they, and which programs against it are still in active trials?

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