Chloride channel protein 2

BE0000765ProteinHumansCLCN2

Voltage-gated and osmosensitive chloride channel. It is acted on by 3 drugs in DrugBank.

Gene name
CLCN2
UniProtKB entry
P51788Swiss-Prot
Cellular location
Cell membrane
Residues / weight
898 residues · 98,534 Da
Also known as
ClC-2

Resolves to

Protein
UniProtP51788UniProt nameCLCN2_HUMAN
Gene
HGNCHGNC:2020NCBI Gene1181GenBank2570864GeneCardsCLCN2
Pharmacology
IUPHAR/GtoPdb699KEGGhsa:1181
Structure
PDB7XF5PDB7XJAPDB8GQU
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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28+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Chloride channel protein 2, how selective are they, and which programs against it are still in active trials?

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