Glutathione S-transferase Mu 3

BE0000810ProteinHumansGSTM3

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. It is acted on by 5 drugs in DrugBank.

Gene name
GSTM3
UniProtKB entry
P21266Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
225 residues · 26,559 Da
Also known as
2.5.1.18 · GST class-mu 3 · GST5 · GSTM3-3 · hGSTM3-3

Resolves to

Protein
UniProtP21266UniProt nameGSTM3_HUMAN
Gene
HGNCHGNC:4635NCBI Gene2947GenBank306820GeneCardsGSTM3
Pharmacology
KEGGhsa:2947
Structure
PDB3GTU
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione S-transferase Mu 3, how selective are they, and which programs against it are still in active trials?

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