Formimidoyltransferase-cyclodeaminase

BE0000822ProteinHumansFTCD

Folate-dependent enzyme, that displays both transferase and deaminase activity. It is acted on by 3 drugs in DrugBank.

Gene name
FTCD
UniProtKB entry
O95954Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
541 residues · 58,926 Da
Also known as
Formiminotransferase-cyclodeaminase · FTCD · LCHC1

Resolves to

Protein
UniProtO95954UniProt nameFTCD_HUMAN
Gene
HGNCHGNC:3974NCBI Gene10841GenBank6537208GeneCardsFTCD
Pharmacology
KEGGhsa:10841
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Formimidoyltransferase-cyclodeaminase, how selective are they, and which programs against it are still in active trials?

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