Metabotropic glutamate receptor 1

BE0000824ProteinHumansGRM1

G protein-coupled receptor for glutamate. It is acted on by 6 drugs in DrugBank.

Gene name
GRM1
UniProtKB entry
Q13255Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,194 residues · 132,356 Da
Also known as
GPRC1A · MGLUR1

Resolves to

Protein
UniProtQ13255UniProt nameGRM1_HUMAN
Gene
HGNCHGNC:4593NCBI Gene2911GenBank945097GeneCardsGRM1
Pharmacology
IUPHAR/GtoPdb289KEGGhsa:2911
Structure
PDB3KS9PDB4OR2PDB7DGD
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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8GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Metabotropic glutamate receptor 1, how selective are they, and which programs against it are still in active trials?

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