Dihydroxyphenylglycine

DB04228ExperimentalSmall molecule

Dihydroxyphenylglycine: Overview.

Mechanism: Pharmacologically active on Metabotropic glutamate receptor 1 and Metabotropic glutamate receptor 5
Curator reviewed
Formula / weight: C₈H₉NO₄ · 183.1614 g/mol (avg)
Also known as: (S)-3,5-dihydroxyphenylglycine · 3,5-Dihydroxy-L-phenylglycine · DHPG · L-3,5-Dihydroxyphenylglycine · S-DHPG
Code names: J516.528H

Resolves to

Compound

Structure

InChIKeyHOOWCUZPEFNHDT-ZETCQYMHSA-NSMILESN[C@H](C(O)=O)C1=CC(O)=CC(O)=C1

Targets

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Dihydroxyphenylglycine, and which of those have an active Phase 3 trial?

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