Glutamate receptor ionotropic, kainate 5

BE0000828ProteinHumansGRIK5

Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. It is acted on by 2 drugs in DrugBank.

Gene name
GRIK5
UniProtKB entry
Q16478Swiss-Prot
Cellular location
Cell membrane
Residues / weight
980 residues · 109,264 Da
Also known as
EAA2 · Excitatory amino acid receptor 2 · GluK5 · Glutamate receptor KA-2 · GRIK2

Resolves to

Protein
UniProtQ16478UniProt nameGRIK5_HUMAN
Gene
HGNCHGNC:4583NCBI Gene2901GenBank251840GeneCardsGRIK5
Pharmacology
KEGGhsa:2901
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutamate receptor ionotropic, kainate 5, how selective are they, and which programs against it are still in active trials?

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