Glutamate receptor ionotropic, kainate 3

BE0000832ProteinHumansGRIK3

Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. It is acted on by 2 drugs in DrugBank.

Gene name
GRIK3
UniProtKB entry
Q13003Swiss-Prot
Cellular location
Cell membrane
Residues / weight
919 residues · 104,036 Da
Also known as
EAA5 · Excitatory amino acid receptor 5 · GluK3 · GluR-7 · GLUR7

Resolves to

Protein
UniProtQ13003UniProt nameGRIK3_HUMAN
Gene
HGNCHGNC:4581NCBI Gene2899GenBank790534GeneCardsGRIK3
Pharmacology
IUPHAR/GtoPdb452KEGGhsa:2899
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
14GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
12+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Glutamate receptor ionotropic, kainate 3, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In