Metabotropic glutamate receptor 4

BE0000833ProteinHumansGRM4

G protein-coupled receptor for glutamate. It is acted on by 3 drugs in DrugBank.

Gene name
GRM4
UniProtKB entry
Q14833Swiss-Prot
Cellular location
Cell membrane
Residues / weight
912 residues · 101,867 Da
Also known as
GPRC1D · MGLUR4

Resolves to

Protein
UniProtQ14833UniProt nameGRM4_HUMAN
Gene
HGNCHGNC:4596NCBI Gene2914GenBank1160183GeneCardsGRM4
Pharmacology
IUPHAR/GtoPdb292KEGGhsa:2914
Structure
PDB7E9HPDB8JD4PDB8JD5
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Metabotropic glutamate receptor 4, how selective are they, and which programs against it are still in active trials?

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