Betaine--homocysteine S-methyltransferase 1

BE0000845ProteinHumansBHMT

Involved in the regulation of homocysteine metabolism. It is acted on by 3 drugs in DrugBank.

Gene name
BHMT
UniProtKB entry
Q93088Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
406 residues · 44,998 Da
Also known as
2.1.1.5

Resolves to

Protein
UniProtQ93088UniProt nameBHMT1_HUMAN
Gene
HGNCHGNC:1047NCBI Gene635GenBank1522683GeneCardsBHMT
Pharmacology
KEGGhsa:635
Structure
PDB1LT7PDB1LT8PDB4M3P
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Betaine--homocysteine S-methyltransferase 1, how selective are they, and which programs against it are still in active trials?

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