Calpastatin

BE0000904ProteinHumansCAST

Specific inhibition of calpain (calcium-dependent cysteine protease). It is acted on by 2 drugs in DrugBank.

Gene name
CAST
UniProtKB entry
P20810Swiss-Prot
Residues / weight
708 residues · 76,572 Da
Also known as
Calpain inhibitor · Sperm BS-17 component

Resolves to

Protein
UniProtP20810UniProt nameICAL_HUMAN
Gene
HGNCHGNC:1515NCBI Gene831GenBank303599GeneCardsCAST
Pharmacology
KEGGhsa:831
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calpastatin, how selective are they, and which programs against it are still in active trials?

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