Eosinophil cationic protein

BE0000908ProteinHumansRNASE3

Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. It is acted on by 3 drugs in DrugBank.

Gene name
RNASE3
UniProtKB entry
P12724Swiss-Prot
Cellular location
Secreted
Residues / weight
160 residues · 18,385 Da
Also known as
3.1.27.- · ECP · Ribonuclease 3 · RNase 3 · RNS3

Resolves to

Protein
UniProtP12724UniProt nameECP_HUMAN
Gene
HGNCHGNC:10046NCBI Gene6037GenBank31077GeneCardsRNASE3
Pharmacology
KEGGhsa:6037
Structure
PDB1DYTPDB1H1HPDB1QMT
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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22+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Eosinophil cationic protein, how selective are they, and which programs against it are still in active trials?

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