Vitamin K-dependent protein S

BE0000943ProteinHumansPROS1

Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It is acted on by 7 drugs in DrugBank.

Gene name
PROS1
UniProtKB entry
P07225Swiss-Prot
Cellular location
Secreted
Residues / weight
676 residues · 75,122 Da
Also known as
PROS

Resolves to

Protein
UniProtP07225UniProt namePROS_HUMAN
Gene
HGNCHGNC:9456NCBI Gene5627GenBank190289GeneCardsPROS1
Pharmacology
KEGGhsa:5627
Structure
PDB1Z6CPDB9L20PDB9L54
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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3Clinical trialsTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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6Pfam domainsDomain architecture mapped to Pfam families and clans
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51+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Vitamin K-dependent protein S, how selective are they, and which programs against it are still in active trials?

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