Sodium tetradecyl sulfate is an anionic surfactant used to treat varicose veins of the lower extremities. An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
- Mechanism
- Curator reviewed
Sodium tetradecyl sulfate is a potent toxin for endothelial cells in that brief exposure to even low concentrations are effective in stripping endothelium over a considerable distance and exposing highly thrombogenic endothelium in the process. Diluted sodium tetradecyl sulfate is also able to induce a hypercoagulable state, possibly by selective inhibition of protein C, and can also promote platelet aggregation.
- Primary indication
- For the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves.Curator reviewed · 1 structured indication
- Formula / weight
- C14H29NaO4S · 316.43 g/mol (avg)
- First approval
- Canada, 2014 · United States, 2019
- Also known as
- Sodium tetradecyl sulphate · Sodium tetradecylsulfate · Tetradecyl sodium sulfate
- Brand names
Resolves to
FVEFRICMTUKAML-UHFFFAOYSA-MSMILES[Na+].CCCCC(CC)CCC(CC(C)C)OS([O-])(=O)=OWhat you can answer from here — as of September 12, 2026
Which drugs share a target with Sodium tetradecyl sulfate, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account