Pro-opiomelanocortin

BE0000947ProteinHumansPOMC

Precursor protein of pituitary hormones that are involved in diverse physiological processes, including the regulation of energy balance, stress response, immune function and skin pigmentation. It is acted on by 5 drugs in DrugBank.

Gene name
POMC
UniProtKB entry
P01189Swiss-Prot
Cellular location
Secreted
Residues / weight
267 residues · 29,424 Da
Also known as
Corticotropin-lipotropin · POMC

Resolves to

Protein
UniProtP01189UniProt nameCOLI_HUMAN
Gene
HGNCHGNC:9201NCBI Gene5443GenBank190188GeneCardsPOMC
Pharmacology
KEGGhsa:5443
Structure
PDB4XNHPDB4XPDPDB4Y49
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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15GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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42+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Pro-opiomelanocortin, how selective are they, and which programs against it are still in active trials?

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