Etorphine

DB01497ExperimentalIllicitVet approvedSmall molecule

A narcotic analgesic morphinan used as a sedative in veterinary practice. In certain countries, etorphine is classified as a Schedule 1 drug and hence, in these countries, it can be... Etorphine is only available to the patients under an official prescription.

Mechanism: Etorphine is an agonist at mu, delta, and kappa opioid receptors. It also has a weak affinity for the ORL1 nociceptin/orphanin FQ receptor.
Curator reviewed
Primary indication: Etorphine is only available for its use in veterinary.Curator reviewed
Formula / weight: C₂₅H₃₃NO₄ · 411.5338 g/mol (avg)
Code names: DEA No. 9056 · M99

Resolves to

Compound

UNII42M2Y6NU9OCAS14521-96-1ChEBI4912PubChem26721KEGGC11793

Clinical / RWD

RxNorm2728549

Structure

InChIKeyCAHCBJPUTCKATP-HBDRVVKHSA-NSMILES[H][C@]12CC3=C4C(OC5[C@@]4(CCN1C)[C@]21CC(C(C)(O)CCC)C5(OC)C=C1)=C(O)C=C3

Targets

P35372OPRM1P41143OPRD1P41145OPRK1P41146OPRL1O60858TRIM13P01189POMC

What you can answer from here — as of August 31, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

921Drug interactionsStructured to mechanism, not free text

29+ReferencesStructured and connected to the statements they support

Which drugs share a target with Etorphine, and which of those have an active Phase 3 trial?

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