Natriuretic peptides B

BE0000979ProteinHumansNPPB

Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed:1672777, PubMed:17372040, PubMed:1914098, PubMed:9458824). It is acted on by 1 drug in DrugBank.

Gene name
NPPB
UniProtKB entry
P16860Swiss-Prot
Cellular location
Secreted
Residues / weight
134 residues · 14,726 Da
Also known as
Brain natriuretic factor prohormone · Gamma-brain natriuretic peptide · Iso-ANP · preproBNP · proBNP

Resolves to

Protein
UniProtP16860UniProt nameANFB_HUMAN
Gene
HGNCHGNC:7940NCBI Gene4879GenBank179515GeneCardsNPPB
Pharmacology
KEGGhsa:4879
Structure
PDB1YK1PDB3N56
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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22Clinical trialsTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Natriuretic peptides B, how selective are they, and which programs against it are still in active trials?

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