Tumor necrosis factor ligand superfamily member 13B

BE0000999ProteinHumansTNFSF13B

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. It is acted on by 9 drugs in DrugBank.

Gene name
TNFSF13B
UniProtKB entry
Q9Y275Swiss-Prot
Cellular location
Cell membrane
Residues / weight
285 residues · 31,222 Da
Also known as
B lymphocyte stimulator · B-cell-activating factor · BAFF · BLYS · Dendritic cell-derived TNF-like molecule

Resolves to

Protein
UniProtQ9Y275UniProt nameTN13B_HUMAN
Gene
HGNCHGNC:11929NCBI Gene10673GenBank4761612GeneCardsTNFSF13B
Pharmacology
KEGGhsa:10673
Structure
PDB1JH5PDB1KD7PDB1KXG
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tumor necrosis factor ligand superfamily member 13B, how selective are they, and which programs against it are still in active trials?

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