Calnexin

BE0001011ProteinHumansCANX

Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It is acted on by 7 drugs in DrugBank.

Gene name
CANX
UniProtKB entry
P27824Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
592 residues · 67,568 Da
Also known as
IP90 · Major histocompatibility complex class I antigen-binding protein p88 · p90

Resolves to

Protein
UniProtP27824UniProt nameCALX_HUMAN
Gene
HGNCHGNC:1473NCBI Gene821GenBank186523GeneCardsCANX
Pharmacology
KEGGhsa:821
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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43+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Calnexin, how selective are they, and which programs against it are still in active trials?

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