E-selectin

BE0001074ProteinHumansSELE

Cell-surface glycoprotein having a role in immunoadhesion. It is acted on by 11 drugs in DrugBank.

Gene name
SELE
UniProtKB entry
P16581Swiss-Prot
Cellular location
Cell membrane
Residues / weight
610 residues · 66,655 Da
Also known as
CD62 antigen-like family member E · ELAM-1 · ELAM1 · Endothelial leukocyte adhesion molecule 1 · LECAM2

Resolves to

Protein
UniProtP16581UniProt nameLYAM2_HUMAN
Gene
HGNCHGNC:10718NCBI Gene6401GenBank182048GeneCardsSELE
Pharmacology
IUPHAR/GtoPdb3200KEGGhsa:6401
Structure
PDB1ESLPDB1G1TPDB4C16
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
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9Clinical trialsTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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35+ReferencesStructured and connected to the statements they support
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Which approved drugs act on E-selectin, how selective are they, and which programs against it are still in active trials?

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