P-selectin

BE0001159ProteinHumansSELP

Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It is acted on by 17 drugs in DrugBank.

Gene name
SELP
UniProtKB entry
P16109Swiss-Prot
Cellular location
Cell membrane
Residues / weight
830 residues · 90,819 Da
Also known as
CD62 antigen-like family member P · GMP-140 · GMRP · Granule membrane protein 140 · GRMP

Resolves to

Protein
UniProtP16109UniProt nameLYAM3_HUMAN
Gene
HGNCHGNC:10721NCBI Gene6403GenBank183389GeneCardsSELP
Pharmacology
IUPHAR/GtoPdb3103KEGGhsa:6403
Structure
PDB1FSBPDB1G1QPDB1G1R
Drugs

What you can answer from here — as of September 07, 2019

17DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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17GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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53+ReferencesStructured and connected to the statements they support
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Which approved drugs act on P-selectin, how selective are they, and which programs against it are still in active trials?

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