Tissue factor

BE0001178ProteinHumansF3

Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. It is acted on by 9 drugs in DrugBank.

Gene name
F3
UniProtKB entry
P13726Swiss-Prot
Cellular location
Membrane
Residues / weight
295 residues · 33,067 Da
Also known as
Coagulation factor III · TF · Thromboplastin

Resolves to

Protein
UniProtP13726UniProt nameTF_HUMAN
Gene
HGNCHGNC:3541NCBI Gene2152GenBank339504GeneCardsF3
Pharmacology
KEGGhsa:2152
Structure
PDB1AHWPDB1BOYPDB1DAN
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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9Clinical trialsTrials of drugs acting on it, by phase and status
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tissue factor, how selective are they, and which programs against it are still in active trials?

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